It is hypothesized that IPCDs prevent DVT formation through 2 mechanisms, namely, by decreasing venous stasis and activating fibrinolysis. INTERMITTENT PNEUMATIC COMPRESSION DEVICES 17 - 19 Although IPCDs can offer protection against VTE, 20 - 22 compliance is often suboptimal, 23, 24 and efficacy may vary importantly across various devices. 11, 12 Mechanical prophylaxis with intermittent pneumatic compression devices (IPCDs) is recommended, particularly in populations at high risk of bleeding, 13 - 16 due to the decreased risk of major bleeding and surgical site bleeding associated with IPCDs. Pharmacological options include anticoagulation ( eg, low molecular weight heparin, new oral anticoagulants, or warfarin) and aspirin, but these may increase the risk of bleeding. 9, 10Ĭlinical practice guidelines generally recommend either pharmacological or mechanical VTE prophylaxis. 6 - 8 VTE prophylaxis is recommended for approximately 60% of high-risk surgical patients and for the 40% of hospitalized medical patients at risk for VTE.
In high-risk groups, such as post-operative surgical patients and acutely ill medical patients, 1 - 5 VTE is a leading cause of morbidity and mortality. Venous thromboembolism (VTE), which encompasses deep vein thrombosis (DVT) and pulmonary embolism (PE), is a serious potential complication in hospitalized patients.
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